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Product Name
Human IGSF8 (His Tag) recombinant protein
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Description
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
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Protein name
Immunoglobulin superfamily member 8
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Protein short names
CD81P3; PGRL; PG REGULATORY-LIKE PROTEIN; CD316; ESTM34; AU041109; AA033172; R75384; KCT-4; EWI2; EWI-2; CD81 PARTNER 3; LIR-D1
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Uniprot ID
Q969P0
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Gene Name
IGSF8; CD81P3; EWI2; KCT4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human IGSF8 (Q969P0-1) (Met1-Thr579) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human IGSF8 consists of 563 amino acids and predicts a molecular mass of 60 KDa. It migrates as an approximately 63 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human PGRL / IGSF8 Protein (His Tag) SDS-PAGE
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