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Product Name
IL2RG antibody
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Description
IL2RG Rabbit Polyclonal antibody. Positive FC detected in Jurkat cells. Positive WB detected in Jurkat cells, K-562 cells. Observed molecular weight by Western-blot: 42kd
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Tested applications
ELISA, WB, FC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CD132 antibody; IL 2 receptor subunit gamma antibody; IL 2R subunit gamma antibody; IL 2RG antibody; IL2RG antibody; IMD4 antibody; p64 antibody; SCIDX antibody; SCIDX1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IL2RG recombinant protein (Accession Number: NM_000206). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:111734(IL2RG antibody) at dilution of 1:400
1X10^6 Jurkat cells were stained with 0.2ug IL2RG antibody (Catalog No:111734, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
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Background
The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL2RA), beta (IL2RB), and gama (IL2RG). IL2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
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