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Human TLR3 Recombinant protein (His tag)

Cat.#: 513650

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human TLR3 Recombinant protein (His tag)
  • Documents
  • Description
    Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. {PubMed:12471095, PubMed:12539043, PubMed:16043704, PubMed:16144834, PubMed:16720699, PubMed:16858407, PubMed:17178723, PubMed:18172197, PubMed:22611194}.
  • Protein name
    Toll-like receptor 3
  • Uniprot ID
    O15455
  • Gene Name
    TLR3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human TLR3 (NP_003256.1) 1-348 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human TLR3 SDS-PAGE

    Recombinant human TLR3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"