-
Product Name
Human TGFB1/TGFB recombinant protein
- Documents
-
Description
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
-
Protein name
transforming growth factor beta 1(TGFB1)
-
Protein short names
TGFB
-
Uniprot ID
P01137
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human TGFB1/TGFB Ala279-Ser390 is expressed.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human TGFB1/TGFB recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"