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Product Name
Human TGFB1/TGFB (His tag) recombinant protein
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Description
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
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Protein name
transforming growth factor beta 1(TGFB1)
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Protein short names
TGFB
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Uniprot ID
P01137
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TGFB1/TGFB Leu30-Ser390 is expressed
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TGFB1/TGFB (His tag) recombinant protein
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