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Product Name
Human TGF-beta 1/TGFB1 recombinant protein
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Protein name
Transforming growth factor beta-1
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Protein short names
CED; TGF-BETA 1; TGFBETA1; DPD1; TGF-BETA1; TGFBETA; TGFB1; LAP; TGFB; TGFB-1
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Uniprot ID
P01137
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Gene Name
TGFB1; TGFB
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Source/Expression Host
CHO Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the active form of human/rhesus/canine TGFβ1 (NP_000651.3) (Ala 279-Ser 390) was expressed and purified. Human, Rhesus and Canine TGFβ1 sequences are identical.
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Protein Species
Human
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Molecular weight
The recombinant human/rhesus/canine TGFβ1 consists of 112 amino acids and has a calculated molecular mass of 12.8 kDa. it migrates as an approximately 13 & 26 kDa band in reduced and non-reduced SDS-PAGE respectively, corresponding to the monomer and homodimer.
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Purity
> 95 % as determined by HPLC.
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Activity
Measured by its ability to inhibit cell proliferation of Mv-1-lu mink lung epithelial cells.
The ED50 for this effect is typically 0.04-0.2 ng/mL. -
Validations
Human / Rhesus / Canine TGF-beta 1 / TGFB1 Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"