Anti-TGF beta 1 (3E7) Mouse antibody

Anti-TGF beta 1 (3E7) Mouse antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TGF beta 1 (3E7) Mouse monoclonal antibody

WB, IHC-P, FC

Human

Mouse IgG1

Antigen: Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli.

Monoclonal

Purified antibody in PBS with 0.05% sodium azide

Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.P01137.This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease