• Human SNX17 Recombinant protein (GST tag)

Human SNX17 Recombinant protein (GST tag)

Cat.#: 512977

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Product Information

  • Product Name
    Human SNX17 Recombinant protein (GST tag)
  • Documents
  • Description
    Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). {PubMed:15121882, PubMed:15769472, PubMed:16712798, PubMed:19005208, PubMed:21512128, PubMed:22492727}.
  • Protein name
    Sorting nexin-17
  • Protein short names
    KIAA0064
  • Uniprot ID
    Q15036
  • Gene Name
    SNX17; KIAA0064
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    17-226 aa encoded by NM_014748 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human SNX17 SDS-PAGE

    Recombinant human SNX17 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"