Human RGMA/RGM (His tag) recombinant protein

Human RGMA/RGM (His tag) recombinant protein

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Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

repulsive guidance molecule family member a(RGMA)

RGM

Q96B86

E.coli

A DNA sequence encoding the Human RGMA/RGM Pro169-Gly422 is expressed with a 6His tag at the N-terminus.

Human

>95% as determined by SDS-PAGE.