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Product Name
Human RGMA (His Tag) recombinant protein
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Protein name
Repulsive guidance molecule A
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Protein short names
C230063O06; RGM; MGC38550; MGC69915; BC059072
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Uniprot ID
Q96B86
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Gene Name
RGMA; RGM
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human RGMA isoform 3 (NP_064596.2) (Met 1-Gly 422), without the C-terminal pro peptide, was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
Human RGMA consists of 450 amino acids. The signal peptide of RGMA is from amino acid 1 to 47. It contains two propeptides, namely from amino acid 48 to 168 and from amino acid 425 to 450. At low pH, the pro-peptide is autocatalytically cleaved and the two chains remain linked via two disulfide bonds.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human RGMA Protein (His Tag) SDS-PAGE
Lane 1: Marker, Lane 2: RGMA
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