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Product Name
Human NPL Recombinant protein (GST tag)
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Description
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity).
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Protein name
N-acetylneuraminate lyase
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Protein short names
C1orf13
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Uniprot ID
Q9BXD5
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Gene Name
NPL; C1orf13
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NPL (NP_110396.1) 1-193 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NPL SDS-PAGE
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