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Product Name
Human NGF/NGFB recombinant protein
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Description
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
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Protein name
nerve growth factor(NGF)
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Protein short names
NGFB
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Uniprot ID
P01138
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human NGF/NGFB Glu19-Ala241 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human NGF/NGFB recombinant protein
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