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  • Human IL17A/CTLA8/IL17 (His tag) recombinant protein

Human IL17A/CTLA8/IL17 (His tag) recombinant protein

Cat.#: 519583

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Product Information

  • Product Name
    Human IL17A/CTLA8/IL17 (His tag) recombinant protein
  • Documents
  • Description
    Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
  • Protein name
    interleukin 17A(IL17A)
  • Protein short names
    CTLA8; IL17
  • Uniprot ID
    Q16552
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL17A/CTLA8/IL17 Gly24-Ala155 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL17A/CTLA8/IL17 (His tag) recombinant protein

    Human IL17A/CTLA8/IL17 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"