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  • Human IL-35 (Fc tag) recombinant protein

Human IL-35 (Fc tag) recombinant protein

Cat.#: 519844

Special Price 265.0 USD

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Product Information

  • Product Name
    Human IL-35 (Fc tag) recombinant protein
  • Documents
  • Description
    Interleukin-35 is a newest and potent suppressive cytokine of the IL-12 family. Unlike other members of the IL-12 family which are produced mainly by antigen-presenting cells (APCs), IL-35 has been identified as a potentially immunosuppressive cytokine primarily produced by regulatory T (Treg) cells, and to a lesser extent by activated dendritic cells and macrophages. IL-35 is composed of the IL-12 p35 subunit and the IL-27 Epstein–Barr virus-induced protein 3 (EBI3) subunit. IL-35 plays an important role in many disease models and has been recently shown to have additional functions aside from inhibition of proliferation, including inducing its own expression in non-Treg cells.
  • Protein name
    Interleukin-35
  • Uniprot ID
    Q14213&P29459
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL-35 Arg21-Lys229&Arg23-Ser219 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL-35 (Fc tag) recombinant protein

    Human IL-35 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"