Anti-IL27 antibody

Cat.#: 142361

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Product Information

  • Product Name
    Anti-IL27 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human IL27
  • Tested applications
    WB, ELISA
  • Species reactivity
    Human IL-27
  • Alternative names
    IL30 antibody; IL27A antibody; IL-27A antibody; IL27p28 antibody; p28 antibody; Il30 antibody; IL-27p28 antibody; IL-27 antibody; EBI3 antibody; IL-27B antibody; Ebi3 antibody; EBI-3 antibody; IL-27 antibody; P28 antibody; Il27 antibody; IL27 antibody; IL-27 antibody; IL-27A antibody; IL27p28 antibody; IL-27p28 antibody; Il30 antibody; IL30 antibody; MGC71873 antibody; p28 antibody; p28 antibody; IL-27 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human IL-27 . IL-27 specific IgG was purified by Human IL-27 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 5-20 μg/ml

    ELISA: 0.1-0.2 μg/ml

    This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human IL-27.

  • Validations

    Human IL-27 Western blot (WB) 14687

    Human IL-27 Western blot (WB) 14687

  • Background
    IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells and dendritic cells. IL-27 protein is also referred as the IL-12 p35-related protein, p28, is one subunit of a heterodimeric cytokine complex, and associates with another subunit EBI3 (EBV-induced gene 3), an IL-12 p40-related protein (IL-27B). IL-27 protein is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 protein has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"