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Product Name
Human IGF1/IBP1 recombinant protein
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Description
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
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Protein name
insulin like growth factor 1(IGF1)
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Protein short names
IBP1
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Uniprot ID
P05019
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IGF1/IBP1 Thr52-Ala118 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IGF1/IBP1 recombinant protein
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