NovoPro
Cart 2
  • Human IGF-1 / IGF-I / IGF1 recombinant protein

Human IGF-1 / IGF-I / IGF1 recombinant protein

Cat.#: 503190

Special Price 77.1 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human IGF-1 / IGF-I / IGF1 recombinant protein
  • Documents
  • Description
    IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
  • Protein name
    Insulin-like growth factor I
  • Protein short names
    IGF-IB; IGF1A; IGF1; IGF-IA; IGFI; C730016P09RIK; IGF-I; MGF; IGF-1
  • Uniprot ID
    P05019
  • Gene Name
    IGF1; IBP1
  • Source/Expression Host
    Yeast
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IGF1 (NP_001104754.1) (Gly49-Ala118) was expressed.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IGF1 consists 70 amino acids and predicts a molecular mass of 7.7 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human IGF-1 / IGF-I / IGF1 Protein

    Human IGF-1 / IGF-I / IGF1 Protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"