Human ICAM2 (His tag) recombinant protein

Human ICAM2 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

intercellular adhesion molecule 2(ICAM2)

P13598

Human Cells

A DNA sequence encoding the Human ICAM2 Lys25-Gln223 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.