-
Product Name
Human GFRA2/GDNFRB/RETL2/TRNR2 (Fc & His tag) recombinant protein
- Documents
-
Description
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.
-
Protein name
GDNF family receptor alpha 2(GFRA2)
-
Protein short names
GDNFRB; RETL2; TRNR2
-
Uniprot ID
O00451
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human GFRA2/GDNFRB/RETL2/TRNR2 Ser22-Ser441 is expressed with a Fc, 6His tag at the C-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human GFRA2/GDNFRB/RETL2/TRNR2 (Fc & His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"