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Product Name
Mouse GFRA2 (His Tag) recombinant protein
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Description
Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
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Protein name
GDNF family receptor alpha-2
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Protein short names
NRTNR-ALPHA; GFRA2; GDNF RECEPTOR ALPHA-2; TRNR2; GDNFR-BETA; TGF-BETA-RELATED NEUROTROPHIC FACTOR RECEPTOR 2; NTNRA; GDNF FAMILY RECEPTOR ALPHA-2; GDNFR-ALPHA-2; NTNR-ALPHA; GDNF RECEPTOR BETA; RETL2; GFR ALPHA 2; NEURTURIN RECEPTOR ALPHA; GDNFRB
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Uniprot ID
Q3UET6
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Gene Name
Gfra2; Gdnfrb; Trnr2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse GFR?2 (NP_032141.2) (Met 1-Ser 441) without the propeptide was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse GFR?2 consists of 431 amino acids and has a calculated molecular mass of 48.5 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 75 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Mouse GFRA2 / GFR?2 / GDNFRB Protein (His Tag) SDS-PAGE
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