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Product Name
Human GADD45A/DDIT1/GADD45 (His tag) recombinant protein
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Description
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.
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Protein name
growth arrest and DNA damage inducible alpha(GADD45A)
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Protein short names
DDIT1; GADD45
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Uniprot ID
P24522
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human GADD45A/DDIT1/GADD45 Met1-Arg165 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human GADD45A/DDIT1/GADD45 (His tag) recombinant protein
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