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Product Name
Human GADD45A/DDIT1 (His & GST Tag) recombinant protein
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Description
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
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Protein name
Growth arrest and DNA damage-inducible protein GADD45 alpha
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Protein short names
GADD45; RP5-975D15.1; AA545191; DDIT1; GADD45A
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Uniprot ID
P24522
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Gene Name
GADD45A; DDIT1; GADD45
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of human GADD45A (P24522) (Met 1-Arg 165) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human GADD45A/GST chimera consists of 402 amino acids and has a calculated molecular mass of 46.2 kDa. It migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human GADD45A / DDIT-1 Protein (His & GST Tag) SDS-PAGE
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