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Product Name
Human EFNA5/EPLG7/LERK7 (Fc tag) recombinant protein
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Description
Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
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Protein name
ephrin A5(EFNA5)
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Protein short names
EPLG7; LERK7
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Uniprot ID
P52803
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human EFNA5/EPLG7/LERK7 Gln21-Asn203 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human EFNA5/EPLG7/LERK7 (Fc tag) recombinant protein
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