-
Product Name
Anti-EFNA5 antibody
- Documents
-
Description
Rabbit Polyclonal to Mouse EFNA5
-
Tested applications
IHC-P
-
Species reactivity
Mouse Ephrin-A5 / EFNA5
-
Alternative names
AL-1 antibody; Epl7 antibody; RAGS antibody; EFL-5 antibody; LERK-7 antibody; AV158822 antibody; Ephrin-A5 antibody; AF1 antibody; EFL5 antibody; RAGS antibody; EPLG7 antibody; GLC1M antibody; LERK7 antibody; AF1 antibody; AL-1 antibody; AV158822 antibody; EFL5 antibody; EFL-5 antibody; Efna5 antibody; EFNA5 antibody; Ephrin-A5 antibody; Ephrin-A5 antibody; Epl7 antibody; EPLG7 antibody; GLC1M antibody; LERK7 antibody; LERK-7 antibody; RAGS antibody; RAGS antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with purified, recombinant Mouse Ephrin-A5 / EFNA5 . Ephrin-A5 / EFNA5 specific IgG was purified by Mouse Ephrin-A5 / EFNA5 affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
IHC-P: 0.1-2 μg/mL
-
Validations
Ephrin-A5 / EFNA5 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
-
Background
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"