Human CLIC4 (His tag) recombinant protein

Human CLIC4 (His tag) recombinant protein

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Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.

chloride intracellular channel 4(CLIC4)

Q9Y696

E.coli

A DNA sequence encoding the Human CLIC4 Met1-Lys253 is expressed with a 6His tag at the N-terminus.

Human

>95% as determined by SDS-PAGE.