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Product Name
Anti-CLIC4 Rabbit antibody
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Description
CLIC4 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
H1; huH1; p64H1; CLIC4L; MTCLIC antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human CLIC4
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:2000-1:10000
1:100
1:100
1:20
1:20
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Validations
Western blot detection of CLIC4 in Rat Brain,C6,3T3,Hela cell lysates using CLIC4 Rabbit mAb(1:1000 diluted).Predicted band size:29kDa.Observed band size:29kDa.
Immunocytochemistry of CLIC4(green) in Hela cells using CLIC4 Rabbit mAb at dilution 1/50, and DAPI(blue)
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Background
Swiss-Prot Acc.Q9Y696.Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"