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Product Name
Human CLIC4 (His Tag) recombinant protein
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Description
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
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Protein name
Chloride intracellular channel protein 4
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Protein short names
RP23-230K10.1; CLIC4; MC3S5; H1; MTCLIC; D0JMB3; DKFZP566G223; CLIC4L; HUH1; TU-74; P64H1; FLJ38640
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Uniprot ID
Q9Y696
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Gene Name
CLIC4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CLIC4 (Q9Y696-1) (Ala 2-Lys 253) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CLIC4 consisting of 263 amino acids and migrates as an 30 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human CLIC4 Protein (His Tag) SDS-PAGE
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