Human CHGA Recombinant protein (His tag)

Cat.#: 506561

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Product Information

  • Product Name
    Human CHGA Recombinant protein (His tag)
  • Documents
  • Description
    Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.; Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist (PubMed:15326220). Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa (PubMed:15723172 and PubMed:24723458). Can induce mast cell migration, degranulation and production of cytokines and chemokines (PubMed:21214543). Acts as a potent scavenger of free radicals in vitro (PubMed:24723458). May play a role in the regulation of cardiac function and blood pressure (PubMed:18541522). {PubMed:15326220, PubMed:15723172, PubMed:21214543, PubMed:24723458, PubMed:18541522}.; Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. {UniProtKB:P26339}.
  • Protein name
    Chromogranin-A
  • Uniprot ID
    P10645
  • Gene Name
    CHGA
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CHGA (XP_054231265.1) 19-225 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CHGA SDS-PAGE

    Recombinant human CHGA SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"