Human CDKN1A/CAP20/CDKN1/CIP1 (His tag) recombinant protein

Cat.#: 519501

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Product Information

  • Product Name
    Human CDKN1A/CAP20/CDKN1/CIP1 (His tag) recombinant protein
  • Documents
  • Description
    Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A) is a member of the CDI family. CDKN1A is widely expressed in all adult tissues, but low expressed in the brain tissue. CDKN1A can be induced by p53/TP53, mezerein and IFNB1, repressed by HDAC1. CDKN1A may be an important intermediate, by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage, CDKN1A can bind to and inhibit cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
  • Protein name
    cyclin dependent kinase inhibitor 1A(CDKN1A)
  • Protein short names
    CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1
  • Uniprot ID
    P38936
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CDKN1A/CAP20/CDKN1/CIP1 Ser2-Pro164 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CDKN1A/CAP20/CDKN1/CIP1 (His tag) recombinant protein

    Human CDKN1A/CAP20/CDKN1/CIP1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"