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  • Human CDK4 (His tag) recombinant protein

Human CDK4 (His tag) recombinant protein

Cat.#: 518052

Special Price 329.2 USD

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Product Information

  • Product Name
    Human CDK4 (His tag) recombinant protein
  • Documents
  • Description
    Cyclin-Dependent Kinase 4 (CDK4) is a member of the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. CDK4 is a component of Cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. These complexes are major integrators of various mitogenenic and antimitogenic signals. It is shown that CDK4 is responsible for the phosphorylation of retinoblastoma gene product (Rb). Defects in CDK4 are a cause of susceptibility to cutaneous Malignant Melanoma Type 3.
  • Protein name
    cyclin dependent kinase 4(CDK4)
  • Uniprot ID
    P11802
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CDK4 Met1-Glu303 is expressed with a 6His, T7 tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CDK4 (His tag) recombinant protein

    Human CDK4 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"