Human CD40LG/CD40L/TNFSF5/TRAP recombinant protein

Cat.#: 518886

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Product Information

  • Product Name
    Human CD40LG/CD40L/TNFSF5/TRAP recombinant protein
  • Documents
  • Description
    CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.
  • Protein name
    CD40 ligand(CD40LG)
  • Protein short names
    CD40L; TNFSF5; TRAP
  • Uniprot ID
    P29965
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CD40LG/CD40L/TNFSF5/TRAP Met113-Leu261 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CD40LG/CD40L/TNFSF5/TRAP recombinant protein

    Human CD40LG/CD40L/TNFSF5/TRAP recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"