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Mouse CD40L/CD154/TNFSF5 (Fc Tag) recombinant protein

Cat.#: 501660

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Product Information

  • Product Name
    Mouse CD40L/CD154/TNFSF5 (Fc Tag) recombinant protein
  • Documents
  • Description
    Cytokine that binds to TNFRSF5. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching (By similarity).
  • Protein name
    CD40 ligand
  • Protein short names
    RP3-527F8.3; GP39; CD40L; TRAP; CD40-L; RP23-153G22.3; IGM; CD40LG; T-BAM; TNFSF5; LY-62; HIGM1; IMD3; HCD40L; CD154; LY62
  • Uniprot ID
    P27548
  • Gene Name
    Cd40lg; Cd40l; Tnfsf5
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the soluble form of mouse CD40LG (P27548) (Gly 115-Leu 260) was fused with the Fc region of human IgG1 at the N-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse CD40LG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 406 amino acids and has a calculated molecular mass of 44.4 kDa. The apparent molecular mass of the monomer is approximately 50 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 80 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized mouse CD40L-Fc (Cat:501660) at 10 μg/mL (100 μl/well) can bind  biotinylated mouse CD40-Fch (Cat:500358), The EC50 of biotinylated mouse CD40-Fch (Cat:500358) is 33-49 ng/mL.
  • Validations

    Mouse CD40L / CD154 / TNFSF5 Protein (Fc Tag) SDS-PAGE

    Mouse CD40L / CD154 / TNFSF5 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"