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Product Name
Human CD32a / Fc gamma RIIA / FCGR2A (167 Arg, Fc Tag) recombinant protein
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Protein name
Low affinity immunoglobulin gamma Fc region receptor II-a
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Uniprot ID
P12318
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Gene Name
FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Ile 218) of human CD32a (AAA35827.1) was fused with the Fc region of human IgG1 at the C-terminus. It is identical to FCGR2A131H/R in the reference.
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Protein Species
Human
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Molecular weight
The recombinant human CD32a/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 426 amino acids and predicts a molecular mass of 47.3 kDa. As a result of glycosylation, the apparent molecular mass of rh CD32a/Fc monomer is approximately 55 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized human CD32a-Fc (Cat:503883) at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1 with a linear range of 0.625-10 μg/ml. -
Validations
Human CD32a / FCGR2A Protein (167 Arg, Fc Tag) SDS-PAGE
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