Human CD31/PECAM-1 recombinant protein

Cat.#: 503761

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Product Information

  • Product Name
    Human CD31/PECAM-1 recombinant protein
  • Documents
  • Description
    The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
  • Protein name
    Platelet endothelial cell adhesion molecule
  • Protein short names
    GPIIA'; ENDOCAM; C85791; CD31; CD31/ENDOCAM; PECAM-1; PECA1; PECAM; PECAM1
  • Uniprot ID
    P16284
  • Gene Name
    PECAM1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    The mature form of human CD31 (EAW94208.1) extracellular domain (Met1-Lys 601) with five additional amino acids (DDDDK) at the C-terminus was expressed and purified.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CD31 consists of 580 amino acids and has a predicted molecular mass of 65.1 kDa. As a result of glycosylation, the molecular mass of rhCD31 is approximately 115 kDa in SDS-PAGE.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human CD31 / PECAM1 Protein SDS-PAGE

    Human CD31 / PECAM1 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"