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Product Name
Anti-CD31 (5E2) Mouse antibody
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Description
CD31 (5E2) Mouse monoclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human
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Alternative names
Adhesion molecule;CD31;CD31 antigen;CD31 EndoCAM;Endocam;FLJ34100;FLJ58394;GPIIA; GPIIA';PECA1;PECA1_HUMAN;Pecam 1;PECAM 1 CD31 EndoCAM;PECAM;PECAM-1;Pecam1;Platelet endothelial cell adhesion molecule;Platelet/endothelial cell adhesion molecule 1; Platele antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Purified recombinant human CD31 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Immunohistochemical analysis of paraffin-embedded human tonsils using CD31/PECAM-1 (5E2) Mouse mAb.
Western blot detection of CD31 in THP-1 cell lysate using CD31 mouse mAb (1:1000 diluted).Predicted band size: 130KDa.Observed band size: 130KDa.
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Background
Swiss-Prot Acc.P16284.PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"