CD31 antibody

CD31 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CD31 Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 120kD

ELISA, WB, IHC

Human; other species not tested.

CD31 antibody; EndOCAM antibody; FLJ58394 antibody; GPIIA antibody; PECA1 antibody; PECAM 1 antibody; PECAM1 antibody; VEC marker antibody

Mouse IgG2b

This antibody was obtained by immunization of CD31 recombinant protein (Accession Number: XM_011524889). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).