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Product Name
Human CD133 Recombinant protein (GST tag)
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Description
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439). {PubMed:20818439, PubMed:24556617}.
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Protein name
Prominin-1
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Protein short names
PROML1
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Uniprot ID
O43490
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Gene Name
PROM1; PROML1; MSTP061
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
806-856 aa encoded by NM_001145847 was inserted into PGEX-4T vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human CD133 SDS-PAGE
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