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Product Name
Anti-CD133 (8F2) Mouse antibody
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Description
CD133 (8F2) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
Prominin-1;Antigen AC133;Prominin-like protein 1;CD133. antibody
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Isotype
Mouse IgG2b
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Preparation
Antigen: Purified recombinant human Prominin-1 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(Ph 7.4) containing with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/3000
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Validations
Western blot detection of CD133 in CaCo2 cell lysate using CD133 mouse mAb (1:3000 diluted).Predicted band size:133KDa.Observed band size:133KDa
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Background
Swiss-Prot Acc.O43490.This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"