Anti-PROM1 antibody

Anti-PROM1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Mouse PROM1

WB

Mouse PROM1

MCDR2 antibody; RP41 antibody; AC133 antibody; CD133 antibody; MCDR2 antibody; STGD4 antibody; CORD12 antibody; PROML1 antibody; MSTP061 antibody; Prom antibody; AC133 antibody; CD133 antibody; Prom-1 antibody; Proml1 antibody; 4932416E19Rik antibody; prominin 1 antibody; PROM1 antibody; MSTP061 antibody; AC133 antibody; CD133 antibody; CORD12 antibody; PROML1 antibody; RP41 antibody; STGD4 antibody; antigen AC133 antibody; hProminin antibody; hematopoietic stem cell antigen antibody; prominin-like protein 1 antibody; prominin 1 antibody; Prom1 antibody; 4932416E19Rik antibody; AC133 antibody; CD133 antibody; Prom antibody; Prom-1 antibody; Proml1 antibody; antigen AC133 homolog antibody; prominin-like 1 antibody; prominin-like protein 1 antibody

Rabbit IgG

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse PROM1, and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein which belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to play a role in maintaining stem cell properties by suppressing differentiation. CD133 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is proposed to play a role in apical plasma membrane organization of epithelial cells. CD133 is also involved in regulation of MAPK and Akt signaling pathways. Mutations in PROM1 gene have been shown to result in retinitis pigmentosa and Stargardt disease. PROM1 gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Expression of this gene is also associated with several types of cancer.