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Product Name
Human Caspase 1 Recombinant protein (His tag)
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Description
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. {PubMed:15498465, PubMed:7876192}.
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Protein name
Caspase-1
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Protein short names
IL1BC; IL1BCE
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Uniprot ID
P29466
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Gene Name
CASP1; IL1BC; IL1BCE
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CASP1 (NP_150635.1) 1-311 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human Caspase 1 SDS-PAGE
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