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Product Name
Anti-Caspase-1 Rabbit antibody
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Description
Caspase-1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human Caspase-1
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/2000
IHC: 1/50-1/200
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Validations
Immunohistochemical analysis of paraffin-embedded human liver, using Caspase-1 Antibody.
Western blot analysis of Caspase-1 in HeLa cell lysate.
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Background
Swiss-Prot Acc.P29466.Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"