• Human BMPR2/PPH1 (His tag) recombinant protein

Human BMPR2/PPH1 (His tag) recombinant protein

Cat.#: 518118

Special Price 159.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human BMPR2/PPH1 (His tag) recombinant protein
  • Documents
  • Description
    Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
  • Protein name
    bone morphogenetic protein receptor type 2(BMPR2)
  • Protein short names
    PPH1
  • Uniprot ID
    Q13873
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human BMPR2/PPH1 Ser27-Ile151 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human BMPR2/PPH1 (His tag) recombinant protein

    Human BMPR2/PPH1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"