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BMPR2 antibody

Cat.#: 108468

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Product Information

  • Product Name
    BMPR2 antibody
  • Documents
  • Description
    BMPR2 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 120kd,97kd
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    BMP type 2 receptor antibody; BMP type II receptor antibody; BMPR 2 antibody; BMPR II antibody; BMPR2 antibody; BMPR3 antibody; BMR2 antibody; BRK 3 antibody; FLJ41585 antibody; FLJ76945 antibody; PPH1 antibody; T ALK antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BMPR2 recombinant protein (Accession Number: NM_001204). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117203(BMPR2 antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117203(BMPR2 antibody) at dilution of 1:1000

    IP Result of anti-BMPR2 (IP:Catalog No:117203, 4ug; Detection:Catalog No:117203 1:500) with mouse brain tissue lysate 6500ug.

    IP Result of anti-BMPR2 (IP:Catalog No:117203, 4ug; Detection:Catalog No:117203 1:500) with mouse brain tissue lysate 6500ug.

  • Background
    BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. Dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form and 150 kD dimer.
  • References
    • Zeng Y, Liu H, Kang K. Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells. Scientific reports. 5:12098. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"