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Human HDAC8 (GST Tag) recombinant protein

Cat.#: 501269

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Special Price 532.2 USD

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Product Information

  • Product Name
    Human HDAC8 (GST Tag) recombinant protein
  • Documents
  • Description
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
  • Protein name
    Histone deacetylase 8
  • Protein short names
    CDLS5; MRXS6; HDAC8; HD8; CDA07; HDACL1; RPD3; RP23-331B22.1; 2610007D20RIK; WTS
  • Uniprot ID
    Q9BY41
  • Gene Name
    HDAC8; HDACL1; CDA07
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the full length of human HDAC8 isoform 1 (NP_060956.1) (Met 1-Val 377) was expressed, fused with the GST tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human HDAC8/GST chimera consists of 602 amino acids and has a predicted a molecular mass of 68 kDa as estimated in SDS-PAGE under reducing conditions.
  • Purity
    > 88 % as determined by SDS-PAGE
  • Validations

    Human HDAC8 / HDACL1 Protein (GST Tag) SDS-PAGE

    Human HDAC8 / HDACL1 Protein (GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"