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Product Name
Mouse CD64/FCGR1 (His & AVI Tag) recombinant protein
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Description
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
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Protein name
High affinity immunoglobulin gamma Fc receptor I
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Protein short names
AI323638; RP11-439A17.1; FCRI; IGFRC; FCGR1A; IGGHAFC; FLJ18345; FCGR1; FCGR1C; CD64; IGFR1; FCGAMMARI; IGFRB; AV092959; FCGR1B
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Uniprot ID
P26151
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Gene Name
Fcgr1; Fcg1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Pro 297) of mouse FCGR1 (NP_034316.1) was fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse FCGR1 consists of 308 amino acids after removal of the signal peptide and has a predicted molecular mass of 34.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FCGR1 is approximately 45-50 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized mouse CD64-AVI at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.07-0.15 μg/ml. -
Validations
Mouse CD64 / FCGR1 Protein (His & AVI Tag) SDS-PAGE
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