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Rat Erythropoietin / EPO (His Tag) recombinant protein

Cat.#: 502642

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Special Price 353.3 USD

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Product Information

  • Product Name
    Rat Erythropoietin / EPO (His Tag) recombinant protein
  • Documents
  • Description
    Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
  • Protein name
    Erythropoietin
  • Protein short names
    OTTMUSP00000024625; EPO; OTTMUSP00000024626; MGC138142; ERYTHROPOIETIN; MVCD2; EP; OTTMUSP00000024624
  • Uniprot ID
    P29676
  • Gene Name
    Epo
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat EPO (P29676-1) (Met 1-Arg 192) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat EPO comprises 176 amino acids with and has a predicted molecular mass of 20 kDa. It migrates as an approximately 27 kDa band in reduced SDS-PAGE.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    1. Measured by its ability to bind human EPOR-Fc (Cat:504113) in a functional ELISA.
    2. Measured by its ability to bind biotinylated human EPOR-His (Cat:502594) in a functional ELISA.
    3. Measured by its ability to bind mouse EPOR-Fch (Cat:50031-M03H) in a functional ELISA.
    4. Measured by its ability to bind human EPOR & CD131-Fc (Cat:CT010-H02H) in a functional ELISA.
    5. Measured by its ability to inhibit Epodependent proliferation of TF1 human erythroleukemic cells.
    The ED50 for this effect is 2-10ng/mL.
  • Validations

    Rat Erythropoietin / EPO Protein (His Tag) SDS-PAGE

    Rat Erythropoietin / EPO Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"