-
Product Name
Mouse Ephrin B3 / EFNB3 (Fc Tag) recombinant protein
- Documents
-
Description
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
-
Protein name
Ephrin-B3
-
Protein short names
EPLG8; EPHRIN B3 / EFNB3; RP23-56I20.5; ELF-3; EPL8; EPH-RELATED RECEPTOR TRANSMEMBRANE LIGAND ELK-L3; LERK-8; ELK-L3; EFL-6; LERK8; EPH-RELATED RECEPTOR TYROSINE KINASE LIGAND 8; EFL6; EPHRIN-B3; NLERK-2
-
Uniprot ID
Q543Q7
-
Gene Name
Efnb3
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the mouse Efnb3 (NP_031937.1) (Met1-Ala227) was expressed with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Mouse
-
Molecular weight
The recombinant mouse Efnb3 consists 438 amino acids and predicts a molecular mass of 48.8 kDa.
-
Purity
> 95 % as determined by SDS-PAGE.
-
Validations
Efnb3 protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"