-
Product Name
Mouse Cystatin 7 / CST7 (Fc Tag) recombinant protein
- Documents
-
Description
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
-
Protein name
Cystatin-F
-
Protein short names
MGC151424; CST7; CMAP; CYSTATIN F; RP23-156P22.1; MGC151426
-
Uniprot ID
O89098
-
Gene Name
Cst7
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the mouse CST7 (O89098) (Met1-Gln144) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Mouse
-
Molecular weight
The recombinant mouse CST7 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 367 amino acids and has a predicted molecular mass of 41.4 KDa. The apparent molecular mass of the protein is approximately 42 KDa in SDS-PAGE under reducing conditions due to glycosylation.
-
Purity
> 93 % as determined by SDS-PAGE
-
Activity
Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC, R&D Systems, Catalog # ES008.
The IC50 is < 6 nM. -
Validations
Mouse Cystatin 7 / CST7 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"