Anti-Cystatin 7 / CST7 antibody

Cat.#: 102593

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Product Information

  • Product Name
    Anti-Cystatin 7 / CST7 antibody
  • Documents
  • Description
    Mouse monoclonal to Cystatin 7 / CST7
  • Tested applications
    WB
  • Species reactivity
    Human Cystatin-F / Cystatin-7
    No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
  • Alternative names
    Cmap antibody; CMAP antibody; CST7 antibody; Cst7 antibody; Cystatin F antibody; Cystatin F antibody; MGC151424 antibody; MGC151426 antibody; RP23-156P22.1 antibody; CMAP antibody; Cmap antibody
  • Immunogen
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CST7 (rh CST7; NP_003641.2; Met 1-His 145). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
  • Clonality
    Monoclonal
  • Formulation
    0.2 μm filtered solution in PBS with 5% trehalose
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 2-10 μg/mL

  • Validations

    Cystatin 7 / CST7 Antibody, Mouse MAb, Western blot

    Cystatin 7 / CST7 Antibody, Mouse MAb, Western blot

  • Background
    The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"