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Product Name
Cyclophilin B antibody
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Description
Cyclophilin B Mouse Monoclonal antibody. Positive IHC detected in human pancreas cancer. Positive WB detected in Hela cells, HepG2 cells, U-937 cells. Observed molecular weight by Western-blot: 24kD
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Cyclophilin B antibody; CYP S1 antibody; CYPB antibody; PPIase B antibody; Rotamase B antibody; S cyclophilin antibody; SCYLP antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of Cyclophilin B recombinant protein (Accession Number: NM_000942). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107225(PPIB antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:107225(PPIB antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:107225(PPIB antibody) at dilution of 1:50 (under 40x lens)
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Background
PPIB, also named as CYPB, SCYLP, PPIase B and CYP-S1, belongs to the cyclophilin-type PPIase family and PPIase B subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes.
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